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  • labs@skims.ac.in

DEPARTMENT OF IMMUNOLOGY & MOLECULAR MEDICINE

FACULTY

: Dr. Zafar Amin Shah, Professor & Head

: Dr. Roohi Rasool, Associate Professor

: Dr. Dil Afroze, Associate Professor

Departmental Activities & Patient Care Services

This department has been established as a super specialty discipline in 1982. General activities of this department include routine as well as advanced laboratory services to the patients. The department takes pride in having well established immunodiagnostic, Radioimmunoassay and Molecular diagnostic laboratories. It is the only BRITT certified radio immune assay laboratory in the state of J&K. Estimation of thyroid, fertility, metabolic and other hormones and metabolites by RIA is a matter of routine in the department. Investigations like detection and typing of Myelomas, autoimmune disorders, and cancer markers, HLA Typing and Cross match testing for renal transplant patients and HLA B27/DR-2/4 detection for ankylosing spondylitis and related diseases are also provided on routine basis.

Molecular diagnostic facilities for diagnosis of Mycobacterium tubercular infection has become a matter of routine in this department. Detection of JAK-2 mutations in haemopoitic disorders is now carried out routinely. Tests for various allergic disorders like SPT, patch testing, autologous serum tests, drug sensitivity & desensitization and Immunotherapy to allergic patients are now done routinely. Clinical services in the form of allergy clinic are run routinely.

ICTC (Integrated Counseling & Testing Centre) for HIV is an integral part of the department. Flowcytometry related tests for HIV positive patients is a matter of routine.

The department also caters to molecular diagnosis, evaluation and prenatal counseling of genetically inherited diseases. Genetic analysis of dystrophin gene in Duchene Muscular Dystrophy patients and affected families is being done. Karyotyping is now done on a routine basis.

Academic activities

The department is actively involved in various academic activities of the institute. The department has a full time M.Sc. MLT & Ph.D programme in Immunology & Molecular Medicine. Many DM/MD/MS students are pursuing their research projects in the department at present.

Research Projects awarded to the faculty of the department.

a) Genetic basis for HIV-1 transmission, resistance and disease progression & polymorphism in MHC genes. - Prof. Mushtaq A Siddiqi

b) Elucidation of genetic alterations in pathogenesis of Prostate cancer- Prof. Mushtaq A Siddiqi

c) Study of genetic alterations in Multiple myeloma- Dr. Zafar A Shah

d) Monitoring of immune markers of graft rejection: a comprehensive study in live-related donor renal transplantation. - Dr. Roohi Rasool

e) DNA HLA typing of highly conserved Kashmiri ethnic population --Dr. Roohi Rasool

f) Assessment of Immunogenetic alterations in patients with pulmonary tuberculosis. – Dr. Dil Afroze

g) Study of genetic alterations in Colorectal Cancer. – Dr. Safiya Abdullah

h) Evaluation of genetic polymorphism in gastric carcinoma. – Dr. Dil Afroze


FACULTY





DR. ZAFAR AMIN SHAH

Professor & Head

EDUCATIONAL QUALIFICATIONS
PhD, IVRI, Izatnagar UP (1993)

MEMBERSHIPS / FELLOWSHIPS

  • Indian Immunology Society.

ONGOING RESEARCH PROJECTS

  • Study of genetic alterations in multiple myeloma (Principal Investigator)
  • DNA based HLA typing of Kashmiri Population (Co-Investigator)
  • Immunogenetic alterations in patients with M.tb (Co-Investigator)
  • Genetic basis for HIV transmission, resistance & disease progression (Co-Investigator)

AREAS OF INTEREST

  • Immunodiagnostics, Cancer Immunology / Cancer Genetics


DR. ROOHI RASOOL

Additional Professor

EDUCATION QUALIFICATION
MBBS, Govt. Medical College Srinagar (1994)
MD, SKIMS Deemed University (1999)
DAA (Diploma Allergy & Asthama), CMC Vellore (2007)

MEMBERSHIPS / FELLOWSHIPS

  • Indian Medical Association.
  • Indian Leptospirosis Association.
  • Indian Immunology Society.

ONGOING RESEARCH PROJECTS

  • Monitoring of immune markers of rejection (ICMR) - (Principal Investigator).
  • DNA based HLA typing of Kashmiri Population - DST (Principal Investigator).
  • HLA & Immunogenetics, Allergy & Immunology Cancer Genetics.

AREAS OF INTEREST

  • Allergy, Immunogenetics, Molecular Medicine, Immunodiagnostics, HIV.



DR. DIL AFROZE
Additional Professor


EDUCATIONAL QUALIFICATIONS

  • MSc, Jamia Millia Islamia New Delhi (November 27' 1992)
  • PhD, AIIMS New Delhi ( May 28' 1999)

MEMBERSHIPS / FELLOWSHIPS

  • Life Member of Indian Immunology Society.
  • Fellowship from University Grants Commission as SRF & JRF
  • Graduate Aptitude for test in Engineering Sciences (GATE)(fellow with a percentile score of 94.86)

ONGOING RESEARCH PROJECTS

  • Assessment of immunogenetic alterations in patients with Mycolacterium tuberclosis - PI in the ICMR funded Project.
  • Genetic and epigenetic alterations in the pathogenesis of pancreatic carcinoma in Kashmiri population - Co-I in DST funded project.
  • Analysis of the role of genetic polymorphism in the assessment of response to chemotherapy drugs in patients with Gastric AdenoCarcinoma - PI in ICMR funded project.
AREAS OF INTEREST
  • AUTOIMMUNITY - Role of Immunity & Genetic Auseptibility.
  • CANCER - Immunogenetic & Molecular basis.
  • INFECTIOUS DISESES - Host factors particularly immunogenetic basis/causes.
OTHER INFORMATION
  • ACADEMIC : So far 6 MD/DM?MS and 1 PhD students have received their degrees under my co-supervision besides presently 8 MD/MS/DM/MCH students persuing their degrees under my co-guideship.
  • PATIENT CARE : In-charge of Molecular Diagnostics based detection of Mycobacterium tuberclosis, Dystrophin gene profile for DMD/BMD, Screening for JAK2 V617F mutations and quantitative analysis of HBV and HCV viral load.

Reports Avaliable Online

AFP BR15-3Ag
BR15-3Ag 3 CEA2
CEA2 2 Cortisol
Cortisol 2 FRT4
FT3 GI19-9Ag
GI19-9Ag 2 GI19-9Ag 3
HCG5 hFSH
hFSH 2 hFSH 4
hFSH 5 hGH2
hLH hLH 2
OV125Ag PRL
PRL 2 Prog
Prog 2 PSA-Hyb
PSA-Hyb 2 TBhCG2
Testo Testo 2
Testo 4 TotIgE
TotT3 TotT3 2
TotT3 3 TotT4
TotT4 10 TotT4 2
TotT4 3 TotT4 4
TotT4 5 TotT4 6
TotT4 7 TotT4 8
TotT4 9 TSH
TSH 10 TSH 2
TSH 3 TSH 4
TSH 5 TSH 6
TSH 7 TSH 8
TSH 9 VitdD